It was a bad omen for the Bulls, when Purdue’s Madison Layden knocked down a three pointer on Purdue’s first offensive possession. The Boilermakers had shot 1-for-28 during their first two games of the season, but against Buffalo, they were red hot finishing 11-for-19 from the three point line. Coupled with a noticeable Purdue height advantage, Purdue handed the Bulls an 82–70 loss.
The biggest news from the game was an apparent knee injury to senior forward Summer Hemphill, who drove the length of the court in the third quarter with 5:20 left, only to come up lame.