Buffalo Bills 28, Miami Dolphins 22
Whew doggie, is this an important deal going down -- or going up, as in up north -- in Buffalo. The Dolphins are clinging to the final wild-card spot in the AFC while the Bills, who already lost to Miami in October, are trying to stay relevant in the playoff chase. Buffalo must shut down Jay Ajayi, which, in theory, shouldn't seem too formidable a task, given how much the Dolphins tailback has slowed down recently. That said, stopping the run has been an issue all year for Rex Ryan's defense.