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Buffalo Bills vs. Patriots: 3 Key matchups in Week 16

It’s the biggest game of the season for the Buffalo Bills as they take on the New England Patriots for the second time this season. Their first meeting went New England’s way as they handed Buffalo their first loss, making them 3-1 at the time.

Each team has continued to play well since then and are No. 1 and 2 in the AFC East. New England (11-3) has a slight edge over Buffalo (10-4) but also has the head to head tiebreaker right now.

Should the Bills find a way to win, they will then hope for Miami to beat the Pats while they go on to face the New York Jets in Week 17.