The Buffalo Bills have simply been on fire these past four weeks. After an 0-2 start, they’ve won four straight and have now cracked the top-10 in the NFL’s power rankings.
Another strong running game and stingy defense against Colin Kaepernick and Carlos Hyde were the headlines in this one as the Bills ran away with a 45-16 clobbering of the 49ers. San Francisco only led the game at one point and that was when they started the scoring with a field goal early on.
After that, the Bills completely took over for the rest of the game.