1 - Red zone defense
The Bills sit atop the league when it comes to keeping opponents out of the end zone when they reach Buffalo’s 20-yard line. They’ve allowed just six touchdowns on 18 red zone possessions allowed (33%). On Sunday San Francisco’s offense went 0-for-2 in the red zone against Buffalo as they settled for a pair of field goals. The 49ers are not alone. Baltimore and New England also went O-fer in the red zone against Buffalo.
2 - Passing touchdowns allowed
The pass defense for the Bills may rank near the middle of the pack at 14th in the NFL, but when it comes to passing touchdowns allowed no other NFL club has allowed fewer.