Forward Oumar Niasse and playmaker Evandro could make their Hull debuts after joining the club on Friday.
Markus Henriksen is out with a shoulder injury, but Michael Dawson and Jake Livermore could return from injury and illness respectively.
Bournemouth's Ryan Fraser is fit again following a calf injury, and Marc Wilson should be available after cramp.
However, the Cherries have lost loanee defender Nathan Ake, who has returned to Chelsea.
MOTD COMMENTATOR'S NOTES
Martin Fisher: "Marco Silva has already taken charge of two Hull City matches but this is where the serious stuff starts.