Bournemouth are without defender Marcos Senesi, who will be sidelined until after the international break.
Dominic Solanke played on Saturday despite not training fully last week, while Tyler Adams was named on the bench for the first time this season.
Luton will assess defenders Gabriel Osho and Teden Mengi, who both came off injured against Crystal Palace.
Elijah Adebayo is also a doubt, meaning the Hatters could be missing up to 11 senior players.
MATCH FACTS
Head-to-head
- This will be a first top-flight meeting between Bournemouth and Luton Town.
- The Hatters have lost only one of the past six league encounters (W2, D3).