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The August 25 Lineup Snafu & The Failed Gimmick Of Interleague Play

A Baseball Mystery
Meg Rowley, Baseball Prospectus, October 5, 2017:

On August 25, a bit of baseball history happened; only, hardly anyone noticed. The Red Sox were losing a blowout against the Orioles. To save an arm, first baseman Mitch Moreland pitched the top of the ninth inning. Hanley Ramirez took Moreland's place at first base, replacing designated hitter Chris Young in the lineup. No more Chris Young, no more designated hitter. Normal blowout stuff so far. But in the bottom of the ninth, Young came to the plate and singled. ...

According to RetroSheet, it is the only instance of illegal lineup re-entry in MLB history.