The 20-year-old Devers became the youngest Red Sox player to hit a home run since Tony Conigliaro in 1965.
The impressive home run came a day after the Red Sox acquired infielder Eduardo Nunez in a trade with the Giants, which has created the question of how long Devers will be on the roster.
Devers has done his part to stay, making several solid plays on defense in his debut on Tuesday, and following that up with a homer in his first at-bat on Wednesday.
The left-handed-hitting slugger is ranked as the No.