Mookie Betts, Xander Bogaerts, Brock Holt, Ryan Hanigan, Eduardo Rodriguez and top prospect Yoan Moncada are among the guests who are expected to be in attendance.
Those players and others will be presented with awards that were voted on by the Boston chapter of the Baseball Writers' Association of America.
Bogaerts, coming off a marvelous 2015 season and still just 23 years old, will receive the Red Sox Most Valuable Player Award.
Betts, the club's other 23-year-old blossoming star, will receive the Jackie Jensen Award for spirit and determination.