Orlin Wagner/Associated Press
College basketball oddsmakers seem to have the Purdue Boilermakers pegged, considering they've lost the last seven times they have gone off as underdogs. Purdue is listed as an underdog again for its Midwest Regional semifinal showdown with the Kansas Jayhawks on Thursday night in Kansas City.
Point spread: The Jayhawks opened as 4.5-point favorites; the total is at 156, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)
March Madness betting pick, via OddsShark computer: 80.7-68.7 Jayhawks (College basketball picks on every game)
Why Purdue can cover the spread
The Big Ten regular-season champs opened this tournament with an 80-70 victory over Vermont last Thursday and outlasted Iowa State on Saturday 80-76.