Michigan State is 8-4 against the spread in its last 12 home games, while Oregon is 14-3 ATS in its last 17 road contests. Something has to give when the Spartans and Ducks meet for a rematch of an Oregon victory of last September this Saturday night, this time in East Lansing.
Point spread: This game opened as a pick'em, according to sportsbooks monitored by Odds Shark (line updates and matchup report).
College football pick, via Odds Shark computer: 26.1-24.9 Ducks
Why the Oregon Ducks can cover the spread
Oregon opened this season with a 61-42 victory over Eastern Washington, toying with the Eagles, scoring twice in the first seven minutes of the game and later leading by 26 before taking its foot off the gas.