TCU owns eight wins in its last nine meetings with SMU, but because they've been favored by so much so often, the Frogs are only 3-6 against the spread during that span. TCU will play as a big favorite again when it battles the Mustangs for the Iron Skillet on Friday night in Dallas.
Point spread: The Horned Frogs opened as 24-point favorites, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
College football pick, via Odds Shark computer: 44.8-19.9 Horned Frogs (college football picks on every game)
Why the TCU Horned Frogs can cover the spread
The Frogs are 2-1 on the season following last week's 41-20 victory over Iowa State.