The Oklahoma State Cowboys own the upper hand in the series with the TCU Horned Frogs, going 4-1 both straight up and against the spread over the last five meetings, including a decisive decision last year in Fort Worth. Can the high-scoring Cowboys extend their hold on the Horned Frogs when the teams open Big 12 play Saturday in Stillwater?
College football point spread: The Cowboys opened as 11.5-point favorites, according to sportsbooks monitored by OddsShark (line updates and matchup report).
College football betting pick, via OddsShark computer: 46.2-29.8 Cowboys (College football picks on every game).