Since becoming Big 12 rivals, the Oklahoma State Cowboys own the edge on the West Virginia Mountaineers, winning three of five meetings straight up and going 3-2 against the spread. In what amounts to an elimination game in this season's Big 12 race, Oklahoma State takes on West Virginia on Saturday afternoon.
College football point spread: The Cowboys opened as six-point favorites, according to sportsbooks monitored by OddsShark. (line updates and matchup report available here)
College football betting pick, via OddsShark computer: 49.0-33.8 Cowboys (college football picks on every game available here)
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