Week 3 wasn't great for the Big 12 with reigning champs Oklahoma losing to Ohio State, and Texas suffering a loss on the road at Cal.
Week 4 will be kinder to those two since both are off. Elsewhere, TCU goes for the Iron Skillet on Friday at SMU, and Oklahoma State faces a big road test at undefeated Baylor.
Kansas and Texas Tech join the Sooners and Longhorns on byes.
Also, visit our college football PickCenter page for additional information on these games and many more.
Here are this week's picks in the Big 12:
San Jose State at Iowa State
Saturday, Sept.