Here are our Week 2 Big 12 picks (all times ET). Visit our college football PickCenter page for additional information on these games and many more.
No. 11 Oklahoma State at South Alabama, 8 p.m. ET Friday (ESPN2/WatchESPN)
Trotter: Past Oklahoma State teams might struggle on the road on a Friday against a non-Power 5 opponent. But these are not those Cowboys. Oklahoma State 51, South Alabama 16
Khan: The Cowboys won't mess around and will make quick work of the Jaguars. Oklahoma State 48, South Alabama 10
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