The American League East foes will face each other in Williamsport, Pennsylvania, on Aug. 21, 2022, in the fifth edition of the game held in conjunction with the Little League World Series. It will count as a home game for the Orioles and be televised nationally as ESPN’s Sunday Night Baseball broadcast.
The Orioles and Red Sox were scheduled to appear in the fourth annual edition of the game during the 2020 season before the coronavirus pandemic caused the meeting to be canceled. The Los Angeles Angels and Cleveland Indians played at Williamsport’s Historic Bowman Field on Sunday night, donning LLWS-themed uniforms.