Wolves midfielder Ruben Neves will be out until at least May after suffering a medial collateral ligament injury to his knee against Leeds.
Striker Raul Jimenez begins a two-game ban after being sent off in that match, his second dismissal of the season.
Left-back Lucas Digne is set to return for Aston Villa after missing the loss to Arsenal with a hamstring issue.
He proved his fitness by playing 90 minutes for France in their 5-0 win against South Africa on Tuesday.
LAWRO'S PREDICTION
I'm going for another draw here. Villa have lost 10 of their 12 games against the teams above them in the table so far this season, but they are only one place below Wolves and these two teams are pretty well-matched, quality-wise.