Tottenham's Mousa Dembele is a doubt after picking up an ankle injury in the win at Crystal Palace.
Goalkeeper Michel Vorm could return to the squad but Danny Rose is still absent with a knee injury.
Arsene Wenger has given centre-back Laurent Koscielny a "60% chance" of playing after suffering a knee injury against Leicester.
Alex Oxlade-Chamberlain is fit but Shkodran Mustafi is missing with a thigh problem.
MOTD COMMENTATOR'S NOTES
Guy Mowbray: "Tottenham's best approach would be to forget the title race for one day.
"Park all thoughts of Chelsea and concentrate on winning a derby - to end 21 seasons of St.