Burnley striker Lyle Foster faces a lengthy spell on the sidelines after surgery to address what manager Vincent Kompany describes as a "chronic issue".
Charlie Taylor could return to contention after recovering from a shoulder injury.
However, this game may come too soon for Jordan Beyer, while Nathan Redmond and Luca Koleosho remain out.
Arsenal manager Mikel Arteta hopes to welcome back "a few" unnamed players from injury at Turf Moor.
Emile Smith Rowe, Takehiro Tomiyasu, Gabriel Jesus, Oleksandr Zinchenko and Fabio Vieira all missed the win at West Ham.
MATCH FACTS
Head-to-head
- Burnley's 1-0 win at the Emirates Stadium in December 2020 is their only victory in 17 Premier League matches against Arsenal (D4, L12).