Everton midfielder Allan is expected to be out for several weeks after sustaining a hamstring injury during Wednesday's win at Leicester City.
James Rodriguez is back in contention following a calf injury, while Seamus Coleman is available after missing five games with a hamstring issue.
Arsenal defender Gabriel is suspended as a result of his red card in the draw against Southampton.
Granit Xhaka is also banned, while Thomas Partey remains out.
LAWRO'S PREDICTION
Mikel Arteta is getting a bit of flak but his own Arsenal players have been making things more difficult for him.