Jamie Sterry's penalty sent League Two Hartlepool into the Papa John's Trophy semi-finals, at the expense of League One Charlton Athletic.
The game ended 2-2 after 90 minutes before Sterry struck the decisive spot-kick to give his side a 5-4 win on penalties.
Rotherham also needed penalties to beat Cambridge and Divin Baningime's goal helped Wigan beat Arsenal Under-21s.
Sutton also made it into the last four after a 1-0 win over Harrogate.
Joe Grey put Hartlepool ahead early on, before Mason Burstow and Alex Gilbey turned it around for the League One side after 32 minutes.