Arsenal forward Bukayo Saka has been ruled out of England's games against Australia and Italy because of injury.
The FA confirmed he has withdrawn after being assessed by England's medical team and would not be replaced in the squad, which now has 25 players.
England face Australia on 13 October, before taking on Italy in a European Championship qualifier four days later.
"No, he will not make it," said Gunners boss Arteta after Sunday's game. "He has not trained for a single session."
While he would not disclose the likely length of Saka's spell on the sidelines, Arteta added: "He is not available to play football at the moment.