Atletico Madrid failed to break down Real Betis in a 0-0 draw on Sunday which further reduced their slim chances of catching Barcelona at the top of La Liga, while Las Palmas were relegated after a crushing 4-0 home defeat by Alaves.
Diego Simeone's Atletico moved 11 points behind Barcelona with four games remaining and the unbeaten leaders need one more point to win the title.
With the Europa League semi-final first leg at Arsenal on Thursday in mind, Simeone rotated key players and Betis tried to take advantage.
Javi Garcia missed two excellent chances and Cristian Tello struck the post for the visitors, who extended their club record run of games without conceding a goal to six.