Arsenal must face Manchester City on Sunday without injured quintet Shkodran Mustafi, Danny Welbeck, Lucas Perez, David Ospina and Santi Cazorla.
Manager Arsene Wenger could keep the three-man defence he used for Monday's league win at Middlesbrough.
Manchester City forward Gabriel Jesus is included in the squad, only 10 weeks after breaking a bone in his foot.
John Stones has failed to recover from the muscle injury that ruled him out of last week's game at Southampton.
WHAT THE MANAGERS SAY
Arsenal manager Arsene Wenger: "It's an opportunity to win a trophy this season.