Arkansas fell to 2-5 in Southeastern Conference play on Sunday at No. 11 Missouri.
The Tigers finished with five players in double figures, led by Sophie Cunningham's 22 points, and knocked down 13 3-pointers, cruising to an 88-54 win over Arkansas.
Kiara Williams and Jailyn Mason led the Razorbacks with 14 points each while Malica Monk added 11 on 4 of 12 from the floor. Arkansas shot 33 percent in the loss and was without senior guard Devin Cosper (ankle) for a second consecutive game.
Arkansas' difficult road swing continues with a trip to No. 10 South Carolina on Thursday.