There is just one ranked matchup this week in college football, which opens the door for some major upsets.
Think back to Week 13 of 2009 when six unranked teams won in a week with a single ranked game. Could history repeat itself?
The Heat Index breaks down the top college football and NFL games to watch.
Seahawks at 49ers
Thursday, Oct. 22 | 5:30 p.m. | Channel 5, NFL Network | What to watch for: The Seahawks have clearly taken a step back this season after their home loss to the Panthers. But the 49ers have taken like 10 steps back.