Other than Cal, Arizona’s most success in recent years has come against Colorado. The Wildcats are 7-3 against the Buffaloes since they joined the Pac-12, though two of those losses have come in the past two meetings.
That includes last year’s 34-0 loss in Boulder, but those were very different teams on both sides.
This year, Colorado (0-4, 0-1 Pac-12) is among the worst teams in the country while Arizona (2-2, 0-1) has already doubled its win total from 2021. The UA is favored by 17.5 points, according to DraftKings Sportsbook, its largest spread against an FBS opponent since 2017.