Houston scored four runs in the second, two in the third and another pair in the fourth, chasing Escobar after 3 1/3 innings. Five players collected multiple hits as the Astros won for the sixth time in seven games. Jason Castro drove in three runs, reaching base four times, and Carlos Correa plated a pair. George Springer also reached base four times, collecting a trio of singles.
D-backs first baseman Paul Goldschmidt homered in the first inning, providing their only run until Jean Segura's RBI triple in the eighth.