1. Defending Kyle Shanahan's Offense
Last November, Kyle Shanahan's Falcons picked apart the Cardinals defense with RBs Devonta Freeman and Tevin Coleman rushing for 3 TDs and speedy WR Taylor Gabriel scoring 2 TDs off WR screen passes (35 and 25 yards).
In SF, Shanahan obviuously does not have Matt Ryan, Julio Jones, Taylor Gabriel, Devonta Freeman and Tevin Coleman...however, in those roles he has Brian Hoyer, Pierre Garcon, Marquis Goodwin, Carlos Hyde and Matt Breida.