It took more than a quarter and a half, but the Titans finally broke a scoreless tie with 7:16 left in the first half.
Tennessee mounted a 50-yard drive that was cemented by a 6-yard touchdown run by running back Derrick Henry.
Titans quarterback Marcus Mariota was 2-for-3 passing for 20 yards on the scoring drive.
The Cardinals were trailing, 7-0, with just over 7 minutes remaining in the second quarter.
End 1: Cardinals 0, Titans 0
Both the Cardinals and Titans remain scoreless after one quarter of play at University of Phoenix Stadium on Sunday.