In a game in which there were plenty of big plays, these plays stood out the most. Cast your vote for the play of the game
- Rashad Johnson's first quarter interception- This was the first of many Lions turnovers and set the tone for the Cardinals defense the rest of the game.
- Corey Redding interception- Tipped the Stafford pass and took it back 30 yards to put the Cardinals in great field position, where it would eventually lead to a David Johnson touchdown.
- Palmer 50 yd pass to John Brown- Detroit had just punted and pinned the Cardinals at their own 1 yard line.