As the Arizona Cardinals are set to open up the 2024 regular season on the road against a good Buffalo Bills squad, we will dive into some of the different predictions for the game along with my week one picks.
The Arizona Cardinals come into this game as +6.5-point underdogs, meaning the line has shifted since Monday according to our friends at FanDuel Sportsbook.
Predictions
Arizona Cardinals offense gets moving
With the addition of Marvin Harrison Jr. and Trey Benson, the offensive line looking improved and a full offseason for Kyler Murray with Drew Petzing, the offense should pick up right where they left off.