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Arizona Cardinals open as massive underdogs ahead of matchup with San Francisco 49ers

The Arizona Cardinals were favorites ahead of their loss to the Washington Commanders.

It will likely be the last time they are favorites going into a game until their bye week, barring a complete transformation of things.

In fact, according to our friends at FanDuel Sportsbook ahead of their week five matchup with the San Francisco 49ers, they are +7.5-point underdogs and that feels low.

I mean, last year the average margin of victory in their two games was 17.5 points and while the Niners are hurting, the Cardinals no longer deserve the benefit of the doubt.