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Arizona Cardinals open as massive home underdogs against surging San Francisco 49ers

are coming off their third win of the 2023 NFL season against a then 7-4 Pittsburgh Steelers (+2.5).

Now, the Steelers sit at 7-6 and have lost games decisively against the Cardinals and the terrible New England Patriots (+10)

as well.

So, when the opening lines came out for the Arizona Cardinals against the San Francisco 49ers (-13.5)

, it was not shocking to see that DraftKings Sportsbook had the 49ers as massive favorites, even though the game is at home.

The Cardinals opened as +13.