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NFL Week 1 picks, schedule, odds, injuries, fantasy tips

The Week 1 NFL schedule for the 2023 season is stacked with great matchups, and we've got you covered with what you need to know heading into the weekend. Our NFL Nation reporters bring us the biggest keys to every game and a bold prediction for each matchup.

Additionally, ESPN Stats & Information research provides a big stat to know and a betting nugget for each contest, and our Football Power Index (FPI) goes inside the numbers with a game projection. Analytics writer Seth Walder picks out each matchup's biggest X factor, and fantasy analyst Eric Moody hands out helpful fantasy football intel.