HOUSTON -- Duke Catalon scored three touchdowns and Houston's defense hurried and harassed Heisman favorite Lamar Jackson all night to propel the Cougars to a stunning 36-10 victory Thursday night that dashed No. 3 Louisville's playoff hopes.
Louisville (9-2) entered the game ranked fifth in the College Football Playoff rankings, but was outdone by a Houston team that saw its own playoff hopes foiled by two losses to unranked teams after a 5-0 start.
Things went wrong quickly for the mistake-prone Cardinals when they fumbled the opening kickoff to Houston (9-2).