While the Miami Dolphins and Cincinnati Bengals are playing the first game of the fourth week of the NFL's 2016 season on Thursday night, the Indianapolis Colts will be on a 7.5-hour airplane ride to play the first of Sunday's 13 games.
The Colts will be on their way to London, where they'll play the Jacksonville Jaguars in the opening game of the NFL's 2016 International Series.
For Ryan Kelly, Indianapolis' rookie center from Alabama, it will be his first trip to Europe.
"Obviously, we know what the goal is to go over there and do," Kelly said.