Two weeks into the NFL's 2016 season, eight teams remain undefeated. At least two of those teams will lose in Week 3.
Either the Houston Texans or New England Patriots will be one of the first-time losers. They kick off this week's NFL schedule on Thursday night with the Texans a slight favorite on the Patriots' home field.
Why? The uncertainty at quarterback for New England.
Tom Brady still has two games remaining on his Deflategate suspension. His backup, Jimmy Garropolo, suffered a sprain of the acromioclavicular joint in his throwing shoulder on Sunday, which should leave rookie Jacoby Brissett from North Carolina State as the Patriots' only option at quarterback.