The defending national champion Duke Blue Devils (23-10) will begin their quest for a second straight title as the fourth seed versus the 13th-seeded North Carolina-Wilmington Seahawks (25-7) in the first round of the West Region.
The Blue Devils are consensus favorites versus the Seahawks and have gone 13-1 straight up and 8-6 against the spread as double-digit chalk this season, according to the Odds Shark College Basketball Database.
Point spread: The Blue Devils opened as 9.5-point favorites; the total was 154.5, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
March Madness pick, via Odds Shark computer: 73.