Oklahoma ended the regular season on a seven-game winning streak, going 6-1 against the spread. Clemson, meanwhile, remains undefeated but is just 1-4 ATS over its last five games. The champions of the ACC match up against the champions of the Big 12 in the first national semifinal of this year's College Football Playoff when the Tigers battle the Sooners in the Orange Bowl on New Year's Eve day in Miami.
Orange Bowl point spread: Sooners opened as 1.5-point favorites, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
College football pick, via Odds Shark computer: 43.