The Clemson Tigers are a great rebounding team as of late, going 10-0 straight up and 7-3 against the spread their last 10 times out following outright losses. Coming off an excruciating defeat against Pittsburgh last week, Clemson looks to rebound again when it visits Wake Forest on Saturday afternoon.
Point spread: The Tigers opened as 23.5-point favorites, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)
College football pick, via Odds Shark computer: 41.6-16.6 Tigers (College football picks on every game)
Why the Clemson Tigers can cover the spread
The Tigers were 9-0 on the season, heading toward a repeat performance at the College Football Playoff, but hit a speed bump last week by losing at home to Pitt 43-42 on a field goal in the final seconds.