The Clemson Tigers are 4-0 in their last four meetings with the Virginia Tech Hokies, including a victory in the ACC Championship Game last season, and 3-1 against the spread. In a game that will help decide who wins the ACC this season, the Tigers and Hokies meet for a rematch Saturday in Blacksburg.
College football point spread: The Tigers opened as 5.5-point favorites, according to sportsbooks monitored by OddsShark. (Line updates and matchup report)
College football betting pick, via OddsShark computer: 40.7-31.4 Tigers (College football picks on every game)
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